GenTBL is a tool to generate ambiguous restraints to be used in HADDOCK.
Distance restraints are implemented in HADDOCK to force groups of atoms to be at a specific distance from each other, these are defined using Crystallography and NMR system (CNS) syntax - commonly saved as ambig.tbl.
More information about the definition of restraints can be found in the following papers:
- Bonvin, A. M. J. J., Karaca, E., Kastritis, P. L., & Rodrigues, J. P. G. L. M. (2018). Defining distance restraints in HADDOCK. In Nature Protocols (Vol. 13, Issue 7, pp. 1503–1503). Springer Science and Business Media LLC.
- de Vries, S. J., van Dijk, M., & Bonvin, A. M. J. J. (2010). The HADDOCK web server for data-driven biomolecular docking. In Nature Protocols (Vol. 5, Issue 5, pp. 883–897). Springer Science and Business Media LLC.
To generate a set of ambiguious distance restraints, fill in the information about your interactors in the form below; Active residues (residue numbers) are those that must be involved in the interaction. Passive residues are those that should be involved in the interaction, Partner define to which interactor these set of residues should be paired with.
